Monday 1 December 2014

MRRBIZ News: Frontier Pharma - NSCLC - Identifying And Commercializing First-In-Class Innovation In Non-Small-Cell Lung Carcinoma

The Report Frontier Pharma - NSCLC - Identifying and Commercializing First-in-Class Innovation in Non-Small-Cell Lung Carcinoma provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. - MarketResearchReports.biz


According to the report, growth in the Non-Small Cell Lung Cancer market will be mainly driven by innovative therapies entering the squamous cell carcinoma market segment. Unlike the non-squamous market segment that currently lacks effective treatment, growth in the NSCLC segment will grow at a moderate Compound Annual Growth Rate (CAGR) of approximately 6.6% till 2020. The value of the Non-Small Cell Lung Cancer (NSCLC) market is expected to grow significantly from US$5.1 billion in 2013 to reach a value of US$7.9 billion in 2020 over the forecast period. This growth will be marked across eight developed nations in the world.

To Read Complete Report with Toc: http://www.marketresearchreports.biz/analysis/228987

The Frontier Pharma - NSCLC - Identifying and Commercializing First-in-Class Innovation in Non-Small-Cell Lung Carcinoma report analyzes innovation in NSCLC segment in the context of the current market landscape and overall pipeline activities. It also includes a comprehensive review of the pipeline for first-in-class therapies, deals surrounding the first-in-class products and analyzes molecule types and molecular target by stage of development. The report also focuses and studies the three main NSCLC subtypes such as squamous cell, adenocarcinoma, and large cell carcinoma.

Studies show that currently the NSCLC pipeline has 389 products that are in an active development stage across various other stages in the global market. However, the Non-Small Cell Lung Cancer (NSCLC) market accrues diversity due to the presence of 122 first-in-class products that accounts for around 38% of the overall pipeline therapies in the market. This poses a stark difference between the range of therapies available in the pipeline and those that the market already comprises of.

The global Frontier Pharma - NSCLC - Identifying and Commercializing First-in-Class Innovation in Non-Small-Cell Lung Carcinoma market finding has strategic implications based on a broad range of market participants. This is due to the market and development landscape that effectively favors first-in-class over non-first-in-class innovation and development in several ways, chiefly through greater revenue and faster approval for both small and large market players.

Nevertheless, despite the high attrition rate in the NSCLC segment, various first-in-class therapies that enter into the market have the potential to improve and transform the NSCLC treatment landscape.

Click Here To Download Detail Report: http://www.marketresearchreports.biz/sample/sample/228987

From the perspective of First-in-Class Products in Licensing and Co-development Deals, the report discusses a total of 117 first-in-class products that are in the pipeline but have not been entered into the co-development or licensing deal. Although there is low sample size in the market, deals in the first-in-class NSCLC products occur earlier in development as compared to the non-first-in-class counterparts. The NSCLC products also offer a lucrative investment prospect on average and higher deal values. 

The report analysis shows significant variations in the NSCLC first-in-class targets in alignment to frequent gene mutations. It also identifies the in-depth analysis of the most promising first-in-class targets that are based on different scientific and clinical parameters.


Related Reports:

Frontier Pharma: Breast Cancer - Identifying And Commercializing First-In-Class Innovation: http://www.marketresearchreports.biz/analysis/223632

The Report Frontier Pharma: Breast Cancer - Identifying and Commercializing First-in-Class Innovation provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. - MarketResearchReports.biz

Exceptionally Large and Innovative Pipeline

The breast cancer pipeline is the largest in the pharmaceutical industry with 815 products in active development across all stages. The range of mechanisms of action employed by these compounds is also highly diverse, especially in comparison to the existing market landscape. More pertinently, the degree and proportion of breakthrough innovations in this pipeline is exceptional; GBI Research analysis identified 253 first-in-class programs in the breast cancer pipeline, acting on 176 first-in-class molecular targets. This accounts for some 39% of all products with a disclosed molecular target and is reflective of the high degree of innovation in this indication. This has far-reaching strategic implications for all market participants, as, despite the high attrition rate in breast cancer, it is highly likely many of the first-in-class technologies will reach the market over the coming decade and may transform the clinical and commercial landscape.

Alignment of First-in-Class Molecular Target with Disease Causation
Click Here To Download Detail Reporthttp://www.marketresearchreports.biz/sample/sample/223632

One of the key trends in oncology and in breast cancer in particular over the last decade is the clinical and commercial impact of targeted therapies designed to target proteins in signaling pathways that are frequently mutated in a significant proportion of the patient population. By aligning the molecular targets for therapeutic intervention with disease causation and/or propagation, these therapies limit the systemic cytotoxic effects whilst inhibiting tumor-promoting signaling pathways. Such strategies thereby typically achieve superior efficacy and safety profiles.


Frontier Pharma: Psoriasis - Identifying And Commercializing First-In-Class Innovation: http://www.marketresearchreports.biz/analysis/206412

The Report Frontier Pharma: Psoriasis - Identifying and Commercializing First-in-Class Innovation provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. - MarketResearchReports.biz

Psoriasis is a chronic, inflammatory disease triggered by deregulated Thymus-derived (T) cells, resulting inflammation and benign hyperplasia of keratinocytes within the skin. Manifestations of affected skin are red, thickened plaques with an overlying silver-white scale, which significantly impairs the patient’s physical and mental wellbeing. The primary cause of psoriasis is unknown, as are the mechanisms that lead to immune cells directing inflammatory responses towards the skin. Within the lucrative autoimmune market, the psoriasis market has grown considerably due to the repositioning of all three marketed Tumor Necrosis Factor (TNF) inhibitors: Humira (adalimumab) and Enbrel (etanercept) which were originally approved for rheumatoid arthritis, and also Remicade (infliximab), the first biologic to be approved for Crohn’s disease, an autoimmune disease which largely affects the gastrointestinal system.

Click Here To Download Detail Report: http://www.marketresearchreports.biz/sample/sample/206412

Table of Contents

1 Table of Contents

1.1 List of Tables
1.2 List of Figures

2 The Case for Innovation
2.1 Growing Opportunities for Biologic Products
2.2 Diversification of Molecular Targets
2.3 Innovative First-in-Class Product Developments Remain Attractive
2.4 Changes in the Clinical and Commercial Environment Will be More Favorable to Products That Target Niche Indications and Patient Populations
2.5 Innovation in Psoriasis

For More latest Reports Under Pharmaceutical Market Research Reports Category: http://www.marketresearchreports.biz/category/38

The global pharmaceutical market is almost a trillion dollar industry. The pharmaceutical market has been playing a very important role in the area of scientific advancement and has contributed significantly to economic growth all across the globe. The global pharmaceutical market consists of a wide range of mid-sized, and big companies, and multinational corporations like biopharmaceutical firms, pharmaceutical companies, virtual pharmas, generic manufacturer
biotechnology firms. The pharmaceutical market also includes various service and ancillary support firms which provide raw materials, undertake contract research projects, contract sales, manufacturing technologies, and regulatory guidance.

The global pharmaceutical market is witnessing satisfactory growth owing to factors like high incidence of chronic and contagious diseases, and rising life expectancy. Research and development related investments are also taking place in the pharmaceutical market due to rising demand for innovative and better drugs. An emerging segment in the pharmaceutical market is that of biopharmaceuticals which is extensively applied in proteomics, drug discovery, and genomics.

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