Ovarian Cancer Therapeutics in Asia-Pacific Markets to 2020 - Off-patent Chemo-regimens to Retain Dominance Despite New Launches
Currently, the therapies developmental pipeline is abuzz with activity but the efficacy of these drugs is still below the expected standard. Progress still needs to be made in improving the overall survival rates of patients suffering from OC. Drugs candidates that show the most potential currently are trebananib and olaparib. These two drugs will likely obtain the regulatory nod during the forecast period of this report. Analysts forecast that it will be a while before these drugs are able to achieve a significant degree of market penetration. Moreover, the premium prices of these drugs will further limit their acceptance.
Thus, new drug approvals cannot be listed as a driver for the Asia Pacific ovarian cancer market. Growth will effectively occur as a result of inflationary forces and the general increase in the pervasiveness of ovarian cancer. The report forecasts that the revenues in the APAC OC market will rise at a meager 5.1% CAGR through the forecast period, touching US$417.6 million by 2020.
The report estimates market revenues and size for the period 2013 to 2020 for key markets in the Asia Pacific region, namely, China, India, Japan and Australia. The report begins with the coverage of the disease epidemiology, treatment patterns and algorithms, as well as a detailed analysis of the clinical trials at various stages. A pipeline analysis of the ovarian cancer therapeutics market is yet another vital component of the report.
Findings of the report state that platinum-based chemotherapy—more specifically paclitaxel and carboplatin regimens—is the customary treatment, in the case of ovarian cancer that is sensitive to platinum. This line of treatment is offered in the case of both first-time as well as recurrent ovarian cancer. The initial treatment of the disease has proven to be effective, with the vast majority of patients reporting remission of their disease. However, the analysis also states that nearly all of these cases experience a relapse – ultimately leading to mortality or the emergence of platinum-resistant ovarian cancer (the prognosis for which is currently poor).
The report identifies a wide gap in the current ovarian cancer market for maintenance therapies. A pressing need is also felt for treatment options that are more effective, especially in patients with platinum-resistant OC.
Upcoming Reports:
(1) - Parabens Market - Global Industry Expert Opinions Analysis, Emerging Opportunities, Market Size, Share, Growth Drivers, Market Trends, Statistics And Forecast 2015 - 2020
Para-hydroxybenzoic acid is commonly abbreviated using the term parabens. Parabens belong to the family of alkyl esters of para-hydroxybenzoic acid. Parabens mainly differ in the para position in the benzene ring due to various chemical substitutions. There are various types of parabens or para-hydroxybenzoic acid available. However, methylparaben, ethylparaben, propylparaben, butylparaben, and benzylparaben are the widely marketed parabens. The chemical substitution provides each parabens ester with different solubility and antimicrobial characteristics. As the length of the alkyl chain of the parabens increases the water solubility decreases and the oil solubility increases. Greater the parabens lipid solubility there will be greater penetration of the parabens through epidermis, which is a layer of skin.
Parabens when applied to the skin partially get metabolized in the skin and in subciteanous fat by four carboxyl esterases. The carboxyl esterases metabolize parabens to para-hydroxybenzoic acid and their respective side chains. After the metabolism of parabens, they get easily absorbed in body. They are mainly produced by the etherification of the para-hydroxybenzoic acid with the proper mix of alcohol such as methanol, ethanol or n-propanol. Parabens find a wide range of applications in cosmetics, food and health care industries. They are widely used in products manufactured by cosmetics and heath care industry as it helps in improving the shelf life of various products.
(2) - Hydrogen Market - Global Industry Expert Opinions Analysis, Emerging Opportunities, Market Size, Share, Growth Drivers, Market Trends, Statistics And Forecast 2015 - 2020
The report on the global hydrogen market puts forth the facts that have made this industry a highly flourishing one. It lays emphasis on how the world economy is shifting its focus towards employing hydrogen in the manufacturing processes brought about by the “clean fuel” culture. The hydrogen market at present is the backbone of several industry verticals. The global refinery market uses hydrogen in processes such as petroleum hydro-cracking and hydro-treating.
The common production processes employed in the hydrogen market are electrolysis of water, coal gasification, partial oxidation (mainly of hydrocarbons), and steam reforming of natural gas. Geographically, the report systematically classifies the hydrogen market into Asia Pacific, North America, Europe, and Rest of the World.
(3) - Tire Raw Materials Market - Global Industry Expert Opinions Analysis, Emerging Opportunities, Market Size, Share, Growth Drivers, Market Trends, Statistics And Forecast 2015 - 2020
A tire is an assembly of various components that are built on a drum and then press cured under pressure and heat. Around 200 materials are consumed in the manufacturing process of tires. The primary raw materials used in the production process of tires include natural rubber, synthetic rubber, steel cords, nylon tire cord fabrics, cords, carbon black, rubber chemicals, etc. Tires form an integral part of any automobile and are produced in different sizes and shapes depending on the applications they are used in. The tire industry is highly raw material intensive industry, where the costs of tire raw materials account for about three fourths of the tire industry turnover.
The raw materials used in the manufacturing of tires depend on the type of the tire and its intended applications. Usually tire types that are usually produced include tires for passenger car tires, light truck tires, trucks and bus tires, special vehicle tires and motorcycle tires. The composition of raw materials also depends on the geographical conditions where the proportion of natural rubber and synthetic rubber varies according to the vehicle type and road conditions. With the growth in demand for automobiles across the globe and specifically in Asia Pacific region the demand for tires is expected to grow further and consequently the demand for raw materials.
(4) - Osmium Market - Global Industry Expert Opinions Analysis, Emerging Opportunities, Market Size, Share, Growth Drivers, Market Trends, Statistics And Forecast 2015 - 2020
Osmium is a chemical element that is represented using the symbol Os. Osmium is a hard and brittle metal that has atomic number of 76. Osmium was discovered by Smithson Tennant in 1803. Osmium is a bluish-white transition metal that belongs to the transition group. Osmium belongs to the platinum group which is usually found as trace elements in alloys and in most of the ores. Osmium is the densest occurring element in the nature. Osmium has a blue-gray tint and is a highly stable element. Osmium is a hard metal that remains lustrous even at extremely high temperatures. Osmium has a low compressibility and has high bulk modulus. Powdered osmium when exposed to the air becomes highly toxic in nature. Osmium is highly volatile as well as water soluble in nature.
Osmium powder has typical characteristic smell of that of the osmium tetroxide. However, osmium oxide is non-volatile, black and toxic in nature. There are several specifications provided regarding the use of osmium as it is extremely toxic and thus, has hazardous effect on human health. Osmium is available in a wide range of purity which usually differs depending on its applications. Elemental or metallic forms of osmium usually include rods, wire, granules and pellets. Different sources of osmium offer the metal in varying shapes. Osmium finds a wide range of applications in manufacturing instrument pivots, electrical contacts and fountain pen tips.
